BALTIMORE — Mike Napoli homered and drove in four runs, John Lackey allowed three hits in six innings and the Boston Red Sox spoiled the Baltimore debut of Ubaldo Jimenez by beating the Orioles 6-2 Wednesday night.
David Ortiz hit a two-run homer off Jimenez (0-1) and Dustin Pedroia had four hits for the defending World Series champion Red Sox, now 1-1 after losing to Baltimore on opening day.
Nelson Cruz homered for the second time in two games for the Orioles, who mustered only six hits off Lackey and three relievers.
Jimenez allowed four runs, five hits and three walks in six innings. He struck out six.
Lackey (1-0) gave up two runs, walked one and struck out six. The right-hander is 14-5 with a 3.34 ERA in 24 career starts against Baltimore.
BLUE JAYS 3
ST. PETERSBURG, Fla. — Mark Buehrle allowed four hits over 8 2-3 innings, Jose Bautista homered twice and Toronto beat Tampa Bay.
Buehrle (1-0) struck out 11 and walked one.
Sergio Santos entered after Ben Zobrist had a two-out single off Buehrle in the ninth and walked Evan Longoria. Brett Cecil then struck out pinch-hitter Matt Joyce for his first save.
Bautista put the Blue Jays ahead 1-0 on his first homer of the season, a solo shot off Matt Moore (0-1) in the fourth. He also connected against Josh Lueke during the seventh.
OAKLAND, Calif. — Scott Kazmir shut out his former team into the eighth inning in his Oakland debut, and the Athletics beat the Indians in the first game of a day-night doubleheader.
Alberto Callaspo hit a two-run homer and Yoenis Cespedes, Jed Lowrie and Brandon Moss added RBI hits for the Athletics, who broke out offensively after being shut out Monday in their big league record 10th straight opening loss.
Kazmir (1-0) allowed just three hits and no walks in 7 1-3 scoreless innings, striking out five.
Corey Kluber (0-1) failed to make it out of the fourth inning and lost for the first time in 13 starts since June 27. He gave up five runs and eight hits in 3 1-3 innings.
TIGERS 2, ROYALS 1 (10)
DETROIT — Ian Kinsler homered and drove in the winning run with a single in the 10th inning to lift the Tigers over the Royals.
Max Scherzer pitched eight scoreless innings for the Tigers, but Joe Nathan blew his first save chance since signing with Detroit in the offseason.
Acquired from Texas for Prince Fielder in a November blockbuster trade, Kinsler homered in the fourth and won the game with a line drive to left-center field off Tim Collins (0-1).
Al Alburquerque (1-0) earned the win.
Scherzer allowed four hits and a walk with seven strikeouts.
WHITE SOX 7
TWINS 6 (11)
CHICAGO — Leury Garcia reached on a bunt single in the 11th inning and came home on a balk and a pair of wild pitches by Samuel Deduno, giving the White Sox a win over the Twins.
Before a crowd of just 10,625, Chicago came back from a 6-4 deficit in the ninth on Garcia’s run-scoring single off Glen Perkins and Adam Eaton’s RBI grounder
Ronald Belisario (1-0) pitched 1 1-3 hitless innings for the win.
The game was delayed 4 minutes, 40 seconds during the top of the seventh after Eaton appeared to catch Oswaldo Arcia’s flyball to center and then dropped it when he went to grab the ball from his glove. The play was ruled a catch, but the Twins challenged the call and it was overturned by a replay umpire in New York.
MILWAUKEE — Atlanta pitcher Aaron Harang and the Brewers’ Matt Garza had no-hit bids until Chris Johnson homered with two outs in the seventh inning, sending the Braves to a victory.
Harang (1-0) didn’t allow a hit until Logan Schafer grounded a single leading off the bottom of the seventh.
Making his Braves’ debut, Harang gave up two hits in 6 2-3 innings, struck out three and walked one.
Relievers Luis Avilan, David Carpenter and Craig Kimbrel were hitless, with Kimbrel getting three outs for his second save.
Garza (0-1) made his Milwaukee debut after signing a $50 million, four-year contract as a free agent. He allowed one run and two hits in eight innings, struck out seven and walked none.
NEW YORK — Gio Gonzalez homered in his first start for the second straight season and pitched three-hit ball to lead the Nationals over the Mets.
Ian Desmond also went deep and Jayson Werth had four hits for the Nationals, who followed up their 10-inning comeback on opening day with a more routine victory against one of Gonzalez’s favorite foes. The left-hander struck out six and walked one in six comfortable innings, improving to 6-0 in his last seven starts against New York.
Bartolo Colon (0-1) was touched up for nine hits over six innings in his Mets debut.
Desmond and Gonzalez (1-0) both homered in the fifth against Colon.
MIAMI — Jordan Pacheco had three hits, Jordan Lyles won in his Colorado debut as the Rockies held on for a victory over the Marlins for their first win of the season.
Charlie Blackmon and Michael Cuddyer each had two hits and an RBI for Colorado, which lost the first two games of the season-opening series.
Giancarlo Stanton hit a two-run homer and drove in three runs, all after Miami fell behind 6-1.
Lyles (1-0) was acquired in an offseason trade the sent Dexter Fowler to the Houston Astros. Lyles allowed four runs and five hits in five innings while striking out five and walking one.